AO Research Institute Davos

June 26, 2019 – June 28, 2019

Orthopaedic infections, including fracture-related infection (FRI), periprosthetic joint infection (PJI) and osteomyelitis, remain amongst the most challenging complications in orthopaedic and musculoskeletal trauma surgery. These infections have been convincingly shown to delay healing, worsen functional outcome and incur significant socio-economic costs.

eCM XIX will focus on the key challenges and novel interventions in the fight against orthopaedic infection. The key clinical challenges, including high treatment failure rates, the substantial bone defects created in treating established infection, and the limitations of conventional antibiotic prophylaxis strategies, will be discussed. In addition, host pathogen interactions will be in focus with an emphasis on bone as a niche for infection and the formation of antibiotic and host defence-resistant biofilms. Some emerging concepts in the field of orthopaedic infection will also be introduced, including 3D printing and bacteriophage therapy. These new topics will supplement the more established field of antimicrobial functionalisation of biomaterials.

We look forward to welcoming researchers in basic microbiology, materials science, immunology and biomedical engineering as well as translational research in the field of orthopaedic infection to Davos in 2019.

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